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We’ve been in Columbus spreading the truth about Hemp and CBD since early 2014. Starting up as a mobile booth targeting parades, festivals and community gatherings, the company soon branched out into small-scale distribution and partnering with local retailers. As the business grew, so did the global interest in CBD, and it is now growing faster than ever. We do intend to remain on the cutting edge of this inspiring new industry, so it is necessary to adapt and evolve as new science and sane politics continue to emerge.

However, it is also equally important to remember how we got here, and acknowledge why we have been successful thus far. Ever since the beginning, one thing has been ever presently evident – that providing an honest-to-facts education on cannabinoids & their role within the human body is absolutely central to the success of this business.


People everywhere are hearing about the amazing potential benefits of CBD – and almost always in the form of Marketing. Naturally skeptical, they have many questions, and although there are now many places to buy CBD, there are very few trustworthy sources of information where people can go to educate themselves about this exciting topic. This is where we choose to be different, and this is where we choose to excel. In early December 2016, the Columbus Botanical Depot was born. Working with only the finest lab-tested CBD products available anywhere, we set out first to educate ourselves. This has proven to be an ever unfolding process, as the basic understanding of the endogenous cannabinoid system (ECS) will inspire countless curiosities about Hemp and its potential for enabling wellness on nearly every level of human physiology.


Offering the highest quality, LAB tested products available today. Please call or email us for a customized recommendation to suit your individual needs. Our highly trained and certified staff are here to help answer any and all questions.

Explore our products


Exceptional customer service laced with empathy is what we provide first and foremost. It is our primary mission – to serve the people by understanding the special relationship the body has with cannabinoids, as well as how to best approach supplementation, based on each unique situation.

The Endocannabinoid System


Within the human body is one of science’s newest and most exciting discoveries. The ECS (endo-cannabinoid system) has been shown to be the largest neurotransmitter system in the body. It regulates relaxation, eating, sleeping, and even cognitive function. Phytocannabinoids, or plant-based cannabinoids such as CBD can assist the body’s health and wellness. In fact, all mammilians produce cannabinoids and have an endocannabinoid system that regulates many natural internal functions. The human body will produce its own natural cannabinoids when exercising, meditating, and omega 3 intake. Endocannabinoids are also found in human breast milk and are vital for proper human development.


We are proud to announce the opening of our new CBD Learning Center!
We have partnered with the Cleveland School of Cannabis in order to bring the best educational resources to our community.

CBD News/Videos


“I had horrible wrist pain for months and I ended up getting a cortisone shot which did help quite a bit. The doctor said if the pain didn’t go away completely or came back we would have to talk about surgery. The pain came back and I decided to try Theramu instead of going back to the doctor. So far it has been great at controlling the pain! Looks like I won’t have to have surgery!”


“These treats are awesome! I have 2 older Dachshunds and they love these treats. As they are getting older they seem to have achy joints, and inflammation. This was causing them to want to slow down and not be as active as they used to be. These CBD dog treats help alleviate the joint pain and have them acting like they are 2-3 years younger. “


“Omar Loves his treats Bought these treats hoping that they would help with some aches and pains of him growing older. They seemed to have done the trick. He now jumps in the back of the car instead of taking it slow. One of the other benefits of these treats he now speak 3 or more languages, he is fluent in German Shepard, French Bulldog and Spanish Spaniel. “


“my dogs LOVE these treats…. My 12 year old Lab had a blood clot in his neck, it burst and disappeared. The Vet was shocked at how this could happen. He had been on paw-riffic treats for about 6 weeks. He has no signs of the blood clot. My Pomeranian experienced anxiety, she would not sleep at night. Taking the CBD treats has calmed her. I have seen such an improvement in both of dogs. My fur babies are part of my family, I want them to live a good quality life. With paw- riffic, I hope I get spend many more years with them. “


“A MUST BUY FOR SENIOR PETS! I have a 11 year old senior labradoodle, who had recently become easily fatigued, was eating less, had weight loss, a few lumps, and just over all seemed to be deteriorating. I did some research, and decided to purchase these treats, which ended up being the best decision I’ve made for my ole guy. After 3 days of taking the treats I saw immediate results, it was AMAZING! It was like he was a brand new pup! He was eating, had more energy to play with his younger brother, even had no issues getting from floor to couch. After a month or two the results were even better, he started to gain his weight back, the side lumps had decreased in size, and still he had energy like I had not seen in quit some time. I also decided to try and give an extra treat around July everyday because of his severe anxiety to fireworks, and he was much calmer, he did not pace the house, but simply just lay as if nothing was going on at all! He’s been on the treats for several months now, and is just a brand new dog. I highly recommend this product for anyone with a senior dog that is in decline, any dog with anxiety, or weight gain issues!! Thank you for your help! “


“A great treat for anxious dogs. These treats really work! We have a hyper mid size dog and these help her calm down, much easier for the travelling we have to do with her. Also our other little anxious dog likes them too! And they love the taste too 🙂 I highly recommend them! “

Amy F

I absolutely love these gummies they work well for my back pain and they help me sleep. Keep up the good work guys!


If you have teens suffering from acne, I highly recommend the cbd soaps. Both my son and daughter love the cbd soaps.


Pain Miracle! I suffer from headaches consistently. I wake up with them and go to bed with them. This roller I will pay $30 for any day. It takes my headache away within 5-10 minutes!! Has a refreshing smell of menthol and feels great in the skin. It’s not oily at all.


Bye bye pain I have 2 bones in my foot that did not heal right after breaking them. This roll helps so much!! I used Icy hot for years, which ia like this. However with icy hot after the ” cold feeling” left I was left in pain again. With this I can go hours without it. Super glad I decided to give it a try.


The best of the best CBD. Just got my package, I couldn’t be more happy with this product. The taste is better then I expected and relief within minutes. All around great. I’m sold and cant wait to order more.

Esteban N.

Best cbd crystalline. Takes my pain right away.